Controversy about abacavir and tenofovir
نویسنده
چکیده
In general, the risk of complications such as heart attack, stroke and poor blood circulation increases as people age. Among HIV-positive people, the risk of these complications is heightened compared to HIV-negative people because of the long-term effects of HIV infection. Chronic viral infections can cause inflammation, and ongoing inflammation can affect the health of many organ-systems, including the kidneys, heart and blood vessels. Compounding the effects of ongoing HIV infection, surveys have found that some HIV-positive people tend to have additional risk factors for cardiovascular disease, including tobacco smoking and the injection of illicit substances such as cocaine, heroin and crystal meth.
منابع مشابه
Controversy about abacavir and tenofovir
In general, the risk of complications such as heart attack, stroke and poor blood circulation increases as people age. Among HIV-positive people, the risk of these complications is heightened compared to HIV-negative people because of the long-term effects of HIV infection. Chronic viral infections can cause inflammation, and ongoing inflammation can affect the health of many organ-systems, inc...
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BACKGROUND To investigate pharmacokinetic interactions associated with coadministration of lersivirine with zidovudine, tenofovir disoproxil fumarate (DF)/emtricitabine (Truvada(®)) or abacavir/lamivudine (Epzicom(®)/Kivexa(®)). METHODS Three Phase I, open, crossover studies with two (studies 1 and 3) or three (study 2) treatment periods were conducted in healthy individuals. In study 1, indi...
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